Job Description

Senior Biocurator Location: Pune, India
A Biocurator at Pierian will be part of our Knowledgebase (KB) team that develops the world’s most clinically robust genomic knowledgebase. Biocurators are skilled scientists with strong molecular biology and cancer biology backgrounds who will curate, interpret and represent the data from a variety of sources into logical rules that form the core of our clinical genomic knowledgebase. Their imprint on the knowledgebase will power medical insights for doctors and patients at clinical molecular laboratories around the world.
About Pierian Every year millions of people bet their lives on precision medicine. Pierian is on a mission to make sure that bet pays off. At Pierian we empower progressive health institutions and diagnostic laboratories to build world-class precision medicine programs. Our industry-leading molecular genomics technologies and expertise deliver the most integrated, trusted, and collaborative approach across the clinical care spectrum. From genomic sequencing and biomedical informatics in the laboratory to reporting and decision support at the patient’s bedside, we drive the adoption of genomics in clinical care and accelerate the fight against cancer and other diseases. For more information, visit www.pieriandx.com or @PierianDx on Twitter.
Responsibilities

• Technical/Scientific
  • Comprehend (analyse, conclude) scientific content/clinical studies from different sources such as clinical practice guidelines, drug labels, clinical trials, research articles, reviews, case reports published in cancer and curate clinically significant data.
  • Associate clinical/scientific evidences in a holistic manner to fulfil curation asks such as clinical inferences and write them as rules
  • Demonstrate clear understanding of the product and end-to-end workflow for the given KB team
    • Screening, Curation strategies (all complexity), Review (if trained as reviewer)
    • How rule engine works, how predicates are written
    • How the curated data is used downstream and how it impacts patient care
  • Contribute to designing workflow for new curation strategy or extrapolate existing curation strategies to a similar new scenario
  • Contribute to designing SOPs &/or Work Instruction (WI) generation - ability to present and defend ideas in team or CCC meetings
  • Identify potential risks of process, project or design, and report deviation from SOP or WI
  • Open to self-training and exploring new technologies

• Communications
  • Should be able to communicate issues within a team or across teams with clear background understanding to achieve outcome or conclusions
  • Initiate or engage in clear communication (slack, email and verbal) regarding any blockers/issues with team members, follow-up and conclude
  • Ability to develop the documentation, PowerPoint presentations, flowcharts, diagrams etc. to communicate technical solutions

• Operational
  • Follow/execute daily/weekly tasks till completion based on SOP with ownership and responsibility
    • Self QC of work – demonstrate a high standard with each deliverable
    • Commitment to delivery of day to day tasks and projects involved as per the project timelines - with little supervision from a senior team member or team lead
  • Should demonstrate clear alignment with the team’s release plan
  • Content documentation – document content related approach in a scientific and methodical manner
    • Handle different types of complexities in the workflow
  • Training: Design, document and execute existing or revised training workflows and conduct training as per SOP/WI
  • Demonstrate niche’ expertise where you are the go-to person for specific activities, training etc.
  • Stay up-to-date on product and process trainings required to create quality deliverables at each phase of product life-cycle
  • Ensure compliance with SDLC and QMS processes defined at organization level to meet quality goals
  • Demonstrate strong adherence to Pierian core values

• PhD in genetics, genomics, molecular biology with 1+ years of postdoc or work experience OR
• Masters degree in molecular biology, genetics, biotechnology or biochemistry with 4+ years of work experience
• Experience required: 4-7 years

• Genetic and molecular understanding of the human disease.
• Good understanding of genomic databases and their annotations (For example: GenBank, RefSeq, dbSNP etc).
• Basic understanding of cancer biology and signaling pathways.
• An understanding of bioinformatics analysis to identify variants within genomic data sets is desirable.
• Proficiency in communicating and understanding of genetic variant details.
• An enthusiastic "can-do" mentality with leadership skills, a dedicated team-worker, having good verbal and written communication skills.
• Previous experience as an experimental scientist in applied science or hands-on experience in oncogenomic diagnostic laboratories is a big plus.
• Experience with open source bioinformatics tools and publicly available variant databases is a plus
• Personal initiative and ability to work effectively as part of a team
• Excellent communication skills

• Outstanding career development and learning opportunities
• Competitive compensation depending on experience and skill
• Friendly team and enjoyable working environment
• Flexible working schedule
• Corporate and social events