Research Scientist
Year Ahmedabad, Gujarat, India
Job Description
b'
Division
ZRC BIOLOGY
Job posted on
Apr 09, 2024
Employee Type
C-C6-Confirmed-R&D Executive
Experience range (Years)
5 years - 15 years
Location - Ahmedabad
Education and Professional Experience : PhD or PhD post doc in pharmacokinetics or pharmacology with pharmacometrics subject knowledge or biometry or statistics.
- 1. Sound subject knowledge of pharmacokinetics and clinical pharmacology, good understanding on in vitro and in vivo pharmacokinetics properties and data interpretation.
- 2. Predict the human PK and clinically relevant doses based on non-clinical PK data using an allometry methods.
- 3. Evaluate novel tools and methodology to improve human PK and dose prediction
- 4. To establish in vitro-in vivo correlation to understand mechanism of drug disposition.
- 5. To integrate ADME, in vitro biology and PD results using a modeling and simulation tools. Perform mechanistic PK/PD modeling to build the correlation between PK and PD/efficacy.
- 6. Establish mathematical or imperial modelling using an in vitro ADME data to predict clinical DDI.
- 7. Explore an integration of ADME data in mechanistic PBPK modelling and prediction of human DDI.
- 8. Provide an expert opinion to project team on PK/PD modelling, PBPK modelling and writing a scientific report for regulatory submission.
- 9. Experience on population PK and PK/PD modelling.
- 10. Professional experience in pharmacometrics and PK modelling & simulation, proficiency in WinNonlin or Monolix, NONMEM, R and other modelling & simulation tools.
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Job Detail
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Job IdJD3273595
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IndustryNot mentioned
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Total Positions1
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Job Type:Full Time
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Salary:Not mentioned
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Employment StatusPermanent
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Job LocationAhmedabad, Gujarat, India
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EducationNot mentioned
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ExperienceYear