Dmpk (pre Formulations) Ra/sra

Year    Bengaluru, Karnataka, India

Job Description




DMPK (PRE-FORMULATIONS) RESEARCH ASSOCIATE/ Sr. RESEARCH ASSOCIATE Educational qualifications M.Pharm (Pharmaceutics) Years of experience 3-8 yrs Key Responsibilities

  • Read and understand client pre-formulation
requirements
  • Solid State and Solution State
Characterization (interpretation of DSC, TGA and pXRD etc. data)
  • Solubility assessment in Aqueous and Organic
solvents simulated intestinal and gastric Medias.
  • Bioavailability enhancement of compounds
  • Excipient Compatibility Studies
  • Preclinical formulation development of NCEs
for pharmacokinetic, toxicology, & in vivo efficacy studies.
  • Ability to work with wide variety of excipients,
API and dosage forms
  • Hands-on experience in strategy to come up
with pharmaceutically acceptable salts for NCEs and their characterization and interpretation of the data to propose the suitable salt.
  • Should know the know-how of various
formulations combinations to address the solubility issues for various routes to perform PK studies in preclinical species.
  • Should be able to develop dosage forms for
therapeutic areas like oncology, metabolic disorders, inflammation etc.
  • Should be able to develop HPLC-UV based
methods for conducting formulation analysis under GLP and Non-GLP modes
  • Good knowledge of chromatography


DMPK (PRE-FORMULATIONS) RESEARCH ASSOCIATE/ Sr. RESEARCH ASSOCIATE
  • Preparation of documents such as SOP's for
Laboratory instruments and reports for preformulation studies. Experience required
  • Good scientific knowledge about the role of
pre-formulation in small molecule discovery.
  • Basic knowledge of pharmacokinetics .
  • Knowledge of various excipients and their
permissible limits in preclinical and clinical setups.
  • Handling of HPLC-UV/PDA
  • Liquid chromatography.

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Job Detail

  • Job Id
    JD2917901
  • Industry
    Not mentioned
  • Total Positions
    1
  • Job Type:
    Full Time
  • Salary:
    Not mentioned
  • Employment Status
    Permanent
  • Job Location
    Bengaluru, Karnataka, India
  • Education
    Not mentioned
  • Experience
    Year