Job Description

Job Title:

Executive / Analyst - Reverse Phase Chromatography (RPC)

(2-3 Years Experience - RP Chromatography Mandatory)

Job Summary:

We are looking for a skilled professional with

2-3 years of hands-on experience

in

Reverse Phase Chromatography (RPC / RP-HPLC / RP purification)

for bulk drug/API purification. The candidate will be responsible for operating chromatography systems, executing purification processes, and ensuring compliance with GMP guidelines.

Key Responsibilities:

Chromatography Operations

Perform

Reverse Phase Chromatography (RP)

for purification of APIs, intermediates, and bulk drug substances. Handle

C18/C8 columns

, mobile phase preparation, and gradient operations. Execute purification processes as per batch manufacturing records (BMR/BPR).
?

Equipment Handling

Operate and maintain

prep chromatography systems

(RP-HPLC / RP flash systems). Monitor equipment parameters, troubleshoot issues, and ensure smooth operation. Clean, sanitize, and maintain columns and chromatography instruments.

Process Execution

Prepare mobile phases (water-acetonitrile, water-methanol, buffers). Monitor fractions, collect purified product, and perform in-process testing. Assist in scale-up and optimization of RP purification steps.

Documentation & Compliance

Maintain batch records, logbooks, and purification data as per

GMP

. Follow SOPs, safety protocols, and quality procedures. Coordinate with QA, QC, and Production teams during audits and validations.

Team & Support

Support process development and technical transfer activities. Work with senior chemists to improve yield and purification efficiency.

Required Skills:

Mandatory:

Strong hands-on experience in

Reverse Phase Chromatography (RP)

. Experience working with C18/C8 columns and gradient operations. Knowledge of RP purification principles and fraction collection. Understanding of GMP, safety, and documentation practices. Basic knowledge of RP-HPLC operation and troubleshooting.

Qualification:

B.Sc / M.Sc (Chemistry), B.Pharm / M.Pharm 2-3 years of experience in

API, Bulk Drug, or Pharmaceutical industry

Job Types: Full-time, Permanent

Pay: ?15,000.00 - ?35,000.00 per month

Benefits:

Food provided Health insurance * Provident Fund