US-based startup building next-generation software platforms for regulated life sciences manufacturing and laboratories
(MES, LES, LIMS, Digital Logbooks, AI-driven insights). Our products operate in
GxP-regulated environments
, requiring strong engineering discipline, validation readiness, and security-by-design.
Here, you won't just be a cog in the machine -- you'll be part of building the machine. If you thrive in environments where you can
wear multiple hats
,
roll up your sleeves
, and
see your work through from start to finish
, this is your opportunity to make a real impact.
We're creating a culture of builders, thinkers, and problem-solvers who aren't afraid to challenge the status quo. Your voice will be heard, your ideas will matter, and your contributions will shape the future of our product and the industry.
We're growing fast, and looking for a hands-on Principal Engineer - SaaS &Hybrid Platforms (Life Sciences) who's ready to wear multiple hats and shape the future of digital pharma.
WHAT YOU WILL DO
The
Principal Engineer
is the
technical authority and architectural owner
of our
SaaS and hybrid-deployed platforms
for regulated life sciences manufacturing and laboratory environments. This role defines the long-term technical vision while remaining
deeply hands-on
, ensuring scalability, security, compliance, and operability across
cloud-native, customer-managed, and hybrid environments
.
You will work closely with founders, product leadership, and compliance teams to translate
regulatory and deployment-specific requirements into robust, supportable architecture
, while mentoring engineering leads and enforcing engineering discipline across the organization.
Why This Role Matters
You define architecture that works
both in the cloud and on the factory/lab floor
Your decisions enable
enterprise adoption in highly regulated environments
You balance
startup agility with validated-system rigor
You shape not just the platform--but how it operates in the real world
DUTIES AND RESPONSIBILITIES:
Architecture & Technical Strategy
Own end-to-end architecture for
multi-tenant SaaS and hybrid (cloud + on-prem) deployments
Define deployment patterns supporting
cloud-only, edge, and customer-managed environments
Establish architectural standards for
GxP-compliant platforms
with strict data isolation
Balance long-term architectural integrity with short-term startup delivery needs
Hands-On Engineering
Lead development of
core platform and deployment-critical services
using
Rust, Node.js, and Python
Design
GraphQL schemas and API contracts
that work across disconnected or partially connected environments
Contribute to performance-critical code paths, synchronization services, and upgrade mechanisms
Troubleshoot complex issues involving
distributed, hybrid, and air-gapped systems
Cloud, Hybrid Ops & Compliance
Architect
Azure-native SaaS infrastructure
and
hybrid deployment models
(AKS, private clusters, edge nodes)
Define upgrade, rollback, and version compatibility strategies for hybrid customers
Establish patterns for
secure data synchronization
, offline operation, and conflict resolution
Partner with QA and Security teams to support
validated releases across deployment models
Security, Data & Regulatory Controls
Define security architecture for
SaaS and on-prem installations
(IAM, RBAC, encryption, key management)
Ensure auditability, traceability, and
electronic records compliance
across hybrid environments
Support
SOC 2, ISO 27001, and GxP audits
, including customer-hosted systems
Govern data residency and customer-controlled encryption requirements
Data, AI & Advanced Capabilities
Architect data pipelines that support
centralized SaaS analytics and local/on-prem processing
Guide use of
Vector Databases and AI/ML
in hybrid and regulated contexts
Define safe AI rollout strategies where
model inference may run locally or in the cloud
Ensure explainability, validation readiness, and controlled model updates
Technical Leadership & Governance
Mentor Tech Leads and Senior Engineers across product and platform teams
Lead architecture and design reviews with deployment and operability focus
Act as escalation point for complex customer deployments and production incidents
Partner with Product to align roadmap with deployment and regulatory realities
WHAT YOU WILL BRING
Experience
Minimum of 12 years of software engineering experience
Minimum of 5 years architecture at platform or product level
Education
B.E./B.Tech or M.E./M.Tech in Computer Science or related field
Equivalent experience acceptable
REQUIRED TECHNICAL SKILLS
Core Engineering
Distributed systems and
hybrid SaaS architectures
Strong proficiency in
Rust, Node.js, and/or Python
API design using
GraphQL and REST
Data modeling across SQL, NoSQL, and time-series systems
Frontend Awareness
Architectural understanding of
Angular
for complex, role-based UIs
Experience supporting UI workflows in partially connected environments
Authentication, authorization, multi-tenant and single-tenant isolation
Secure software supply chain and artifact signing
Experience with
regulated, audited, or safety-critical systems
Regulated Industry Experience (Strongly Preferred)
Life Sciences Manufacturing or Laboratory systems (MES, LES, LIMS)
GxP, 21 CFR Part 11, electronic records & signatures
Validation lifecycle (SDLC, IQ/OQ/PQ)
Data integrity principles (ALCOA+)
Soft Skills & Leadership
Strong system-level thinking and decision-making
Ability to communicate complex architecture to technical and non-technical audiences
Pragmatic leadership in startup environments
Comfortable working with global and customer-facing teams
- You'll help design and build a platform from the ground up. Every feature, every decision, every improvement -- you'll be part of it.
Mission-Driven Work
- We're solving critical problems in pharma manufacturing that improve safety, compliance, and efficiency.
Accelerated Growth
- With us, you'll learn faster, stretch your skills, and take on challenges that would take years to access elsewhere.
Startup Energy, Real Impact
- No red tape. No silos. Just smart, motivated people building something meaningful together.
End-to-End Visibility
- Be part of the full journey -- from whiteboard to deployment -- and actually see how your work changes the game.
Build
category-defining products
for regulated life sciences
Work on
cutting-edge AI + vector search
in real-world GxP environments
High ownership, real impact, and direct collaboration with US leadership
Opportunity to influence platform architecture from early stages
Why You'll Love It Here??
Here are some things you will be a part of:
Build foundational products with real-world impact in life sciences.
Work directly with founders and be part of early product leadership.